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Avise SLE

Having difficulty diagnosing rheumatic diseases?
Avise SLE can help!

Our breakthrough diagnostic is designed to Rule-In SLE and Rule-Out other rheumatic diseases to help you establish the most accurate SLE diagnosis. Avise SLE is a 5-marker panel consisting of serological and flow cytometric tests performed using a standard blood specimen, and shipped to our specialized laboratory for processing. Specifically, the panel includes testing of the following markers:

  1. ANA (anti-nuclear antibodies)* — a negative result helps rule-out the possibility of SLE
  2. dsDNA (anti-double stranded DNA antibodies) — a positive result rules-in SLE
  3. AVISE MCV (anti-mutated citrullinated vimentin antibodies) — to rule-out Rheumatoid Arthritis
  4. EC4d

    Using cell-bound complements to rule-in SLE because of their increased performance over soluble complements which helps to accurately and consistently diagnose SLE**.

  5. BC4d

Using the science above, Avise SLE is most impactful when ordered as a first step in patient treatment to help physicians with SLE diagnosis by providing:

  • Efficiency -- 5 individual markers, 1 blood draw
  • Confidence in SLE Diagnosis -- From a panel that rules-in SLE and rules-out other rheumatic diseases
  • Increased Accuracy -- Using CB-CAPs technology to achieve 78% sensitivity and 87% specificity for other diseases/97% specificity for normal/healthy patients.***
  • Convenience -- We provide kits, pay for shipping costs and return test results in 7 business days

Avise SLE Diagnostic Immunology:

  • ANA, dsDNA and AntiMCV are measured using ELISA*
  • EC4d and BC4d are measured using Flow Cytometry

Specimen Collection & Handling Details:

  • Serum (5ml Serum Separator Tube)
  • EDTA blood (10ml)
  • Avise SLE test requisition
  • Overnight shipping in pre-provided Avise kits equipped with frozen coolant cartridge
  • Turnaround time – 7 business days upon receipt
Overcome the current hurdles of SLE diagnosis and help your patients get the answers they deserve by ordering Avise SLE today!